No matter which way you tune your guitar (basic way, harmonics, with a tuning device, or by ear), it is always a good idea to trust your ears.
Some of the things I like to do after tuning include:
If you have just installed new strings on your guitar, especially if it's nylon strings, they will need to be tuned several times before they are finally in tune. Remember to adjust the A-string every time, before tuning the other strings, unless you are using a tuning device.
Important! If you have an acoustic guitar, make sure it is designed for steel strings before installing steel strings on it. If you have a guitar meant for nylon strings, and you install steel strings on it, you can very easily damage the guitar. The bridge will come loose from the body, or in worse case, if you have a guitar of poor quality, the neck can actually break loose from the body.
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